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Video: Compound Annual Growth Rate (CAGR) Definition
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 |
| Date |
Open |
High |
Low |
Close |
Volume |
| 10/09/2026 |
$0.60 |
$0.62 |
$0.56 |
$0.60 |
963.00K | | 10/12/2026 |
$0.59 |
$0.60 |
$0.50 |
$0.51 |
895.10K | | 10/13/2026 |
$0.49 |
$0.50 |
$0.40 |
$0.43 |
1.75M | | 10/14/2026 |
$0.43 |
$0.43 |
$0.32 |
$0.32 |
2.08M | | 10/15/2026 |
$0.31 |
$0.35 |
$0.31 |
$0.35 |
1.33M |
 |
| Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. Co. is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. It is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. | |
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Karyopharm Therapeutics (KPTI) has the following price history information. Looking back at KPTI historical stock prices for the last five trading days, on October 09, 2026, KPTI opened at $0.60, traded as high as $0.62 and as low as $0.56, and closed at $0.60. Trading volume was a total of 963.00K shares. On October 12, 2026, KPTI opened at $0.59, traded as high as $0.60 and as low as $0.50, and closed at $0.51. Trading volume was a total of 895.10K shares. On October 13, 2026, KPTI opened at $0.49, traded as high as $0.50 and as low as $0.40, and closed at $0.43. Trading volume was a total of 1.75M shares. On October 14, 2026, KPTI opened at $0.43, traded as high as $0.43 and as low as $0.32, and closed at $0.32. Trading volume was a total of 2.08M shares. On October 15, 2026, KPTI opened at $0.31, traded as high as $0.35 and as low as $0.31, and closed at $0.35. Trading volume was a total of 1.33M shares.
KPTI Historical Stock Prices By Date:

Below, we examine the compound annual growth rate — CAGR for short — of an investment into Karyopharm Therapeutics shares, starting with a $10,000 purchase of KPTI, and working forward through the historical stock price information to today.
Growth of $10,000.00
Without Dividends Reinvested
|
| Start date: |
10/18/2016 |
|
| End date: |
10/15/2026 |
|
| Start price/share: |
$129.30 |
|
| End price/share: |
$0.35 |
|
| Dividends collected/share: |
$0.00 |
|
| Total return: |
-99.73% |
|
| Average Annual Total Return: |
-44.63% |
|
| Starting investment: |
$10,000.00 |
|
| Ending investment: |
$27.13 |
|
| Years: |
10.00 |
|
|
 |
| Date |
Close |
| 10/09/2026 | $0.60 | | 10/12/2026 | $0.51 | | 10/13/2026 | $0.43 | | 10/14/2026 | $0.32 | | 10/15/2026 | $0.35 |
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