 |
Video: Compound Annual Growth Rate (CAGR) Definition
|
 |
| Date |
Open |
High |
Low |
Close |
Volume |
| 11/26/2025 |
$28.85 |
$29.46 |
$27.84 |
$29.04 |
1.86M | | 11/28/2025 |
$29.30 |
$29.30 |
$28.45 |
$29.20 |
500.60K | | 12/01/2025 |
$28.51 |
$28.55 |
$27.63 |
$27.84 |
1.50M | | 12/02/2025 |
$27.74 |
$27.99 |
$26.81 |
$26.98 |
1.73M | | 12/03/2025 |
$27.15 |
$27.73 |
$26.99 |
$27.49 |
1.20M |
 |
| Agios Pharmaceuticals, Inc. is a biopharmaceutical company. Co. is focused on developing and delivering transformative therapies for patients living with rare diseases. It markets a first-in-class pyruvate kinase (PK) activator for adults with PK deficiency, the first disease-modifying therapy for debilitating hemolytic anemia. Its lead product candidate in its genetically defined disease (GDD) portfolio, PYRUKYND (Mitapivat), is an activator of both wild-type and a variety of mutant pyruvate kinase (PK) enzymes, for the treatment of hemolytic anemias. The Mitapivat is an orally available small molecule and a potent activator of the pyruvate kinase R (PKR) enzymes. | |
 |

Agios Pharmaceuticals (AGIO) has the following price history information. Looking back at AGIO historical stock prices for the last five trading days, on November 26, 2025, AGIO opened at $28.85, traded as high as $29.46 and as low as $27.84, and closed at $29.04. Trading volume was a total of 1.86M shares. On November 28, 2025, AGIO opened at $29.30, traded as high as $29.30 and as low as $28.45, and closed at $29.20. Trading volume was a total of 500.60K shares. On December 01, 2025, AGIO opened at $28.51, traded as high as $28.55 and as low as $27.63, and closed at $27.84. Trading volume was a total of 1.50M shares. On December 02, 2025, AGIO opened at $27.74, traded as high as $27.99 and as low as $26.81, and closed at $26.98. Trading volume was a total of 1.73M shares. On December 03, 2025, AGIO opened at $27.15, traded as high as $27.73 and as low as $26.99, and closed at $27.49. Trading volume was a total of 1.20M shares.
AGIO Historical Stock Prices By Date:

Below, we examine the compound annual growth rate — CAGR for short — of an investment into Agios Pharmaceuticals shares, starting with a $10,000 purchase of AGIO, and working forward through the historical stock price information to today.
Growth of $10,000.00
Without Dividends Reinvested
|
| Start date: |
12/07/2015 |
|
| End date: |
12/03/2025 |
|
| Start price/share: |
$49.26 |
|
| End price/share: |
$27.49 |
|
| Dividends collected/share: |
$0.00 |
|
| Total return: |
-44.19% |
|
| Average Annual Total Return: |
-5.67% |
|
| Starting investment: |
$10,000.00 |
|
| Ending investment: |
$5,579.15 |
|
| Years: |
10.00 |
|
|
 |
| Date |
Close |
| 11/26/2025 | $29.04 | | 11/28/2025 | $29.20 | | 12/01/2025 | $27.84 | | 12/02/2025 | $26.98 | | 12/03/2025 | $27.49 |
|
 |